microRNAs: small molecules with big roles -C. elegans to human cancer
نویسندگان
چکیده
منابع مشابه
MicroRNAs: Small molecules with big roles in neurodevelopment and diseases
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that play important roles in the development and functions of the brain. Extensive studies have revealed critical roles for miRNAs in brain development and function. Dysregulation or altered expression of miRNAs is associated with abnormal brain development and pathogenesis of neurodevelopmental diseases. This review serves to hig...
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MicroRNAs (miRNAs) are small, non-coding regulatory RNAs found in many phyla that control such diverse events as development, metabolism, cell fate and cell death. They have also been implicated in human cancers. The C. elegans genome encodes hundreds of miRNAs, including the founding members of the miRNA family lin-4 and let-7. Despite the abundance of C. elegans miRNAs, few miRNA targets are ...
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ژورنال
عنوان ژورنال: Biology of the Cell
سال: 2008
ISSN: 0248-4900
DOI: 10.1042/bc20070078